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Flumadine Drug Interactions
If you take certain medications with Flumadine, drug interactions could occur that may either decrease the level of the flu medication in your blood or increase your risk of side effects. Some of the medications that may cause negative Flumadine interactions include cimetidine, aspirin, acetaminophen, and the intranasal flu vaccine.
Flumadine® (rimantadine hydrochloride) can potentially interact with several other medicines. Some of these medicines that may lead to Flumadine interactions include:
- Acetaminophen (Tylenol® and many others)
- Aspirin (Bayer® and many others)
- Cimetidine (Tagamet®)
- The intranasal flu vaccine (FluMist™).
The following sections explain in detail the potentially negative interactions that can occur when Flumadine is combined with any of the drugs listed above.
Acetaminophen (Tylenol and Others)
Taking Flumadine with acetaminophen can slightly decrease the level of Flumadine in the blood. It is not known if this is significant enough to decrease the effectiveness of Flumadine.
Aspirin (Bayer and Others)
Taking Flumadine with aspirin can slightly decrease the level of Flumadine in the blood. It is not known if this is significant enough to decrease the effectiveness of Flumadine. However, keep in mind that children and adolescents under age 19 should not take aspirin if they have (or may have) the flu, since aspirin increases the risk of Reye's syndrome.
Cimetidine (Tagamet)
Cimetidine may increase the level of Flumadine in your blood, increasing your risk of Flumadine side effects. Check with your healthcare provider before using these medications together.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD