Flu Home > Flumadine

Flumadine is a medication used to prevent and treat certain types of influenza (the flu). It can shorten the duration of symptoms when you take it at the first signs of the flu, and it may prevent the flu from occurring in the first place. This product is available by prescription only and comes in tablet form. Potential side effects include dizziness, nausea, and insomnia.

What Is Flumadine?

Flumadine® (rimantadine hydrochloride) is a prescription medication used to both treat and prevent certain types of the flu (influenza). When taken at the first signs of the flu, Flumadine shortens the duration of flu symptoms. When taken before a person has the flu (such as during a flu outbreak), Flumadine may not always prevent the flu, but it may help make the flu case more mild.
 
(Click Flumadine Uses for more information, including possible off-label uses.)
 

Who Makes It?

Brand-name Flumadine is manufactured by Forest Pharmaceuticals, Inc. Generic versions are made by various different manufacturers.
 

How Does Flumadine Work?

It is thought that Flumadine works by inhibiting the uncoating of the flu virus, an important step in the replication (the "reproduction") of the virus. Specifically, the medicine inhibits the activity of the influenza virus M2 protein, which forms a channel in the virus membrane. As a result, the virus cannot replicate (make copies of itself) after it enters a human cell.
 
Flumadine is effective only for some influenza A viruses and is not effective against influenza B viruses. Since the "bird flu" or "avian flu" virus (H5N1) is a type of influenza A, it is possible that this drug may work for some strains of this virus. However, many strains of H5N1 influenza are resistant to this medication.
 
For any given year, the predominant flu strain may or may not be susceptible to Flumadine. If the predominant flu strain is not susceptible, this medication should not be used to prevent or treat the flu.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation
Advertisement


Topics

Medications

Quicklinks

Related Channels

eMedTV Links
Copyright © 2006-2017 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.